显著性差异统计分析

 

Correlation Venn heatmap DEPs-Number Volcano Plot Pattern

Proteomic analysis of the rice (Oryza officinalis) provides clues on molecular tagging of proteins for brown planthopper resistance Xiaoyun Zhang, Fuyou Yin, Suqin Xiao, Chunmiao Jiang, Tengqiong Yu, Ling Chen, Xue Ke, Qiaofang Zhong, Zaiquan Cheng and Weijiao Li BMC Plant Biology 201919:30 Dynamic protein corona influences immune-modulating osteogenesis in magnetic nanoparticles (MNPs)-infiltrated bone regeneration scaffolds in vivo. Zhu Y, Jiang P, Luo B, Lan F, He J, Wu Y. Nanoscale. 2019.

火山图(Volcano Plot)在组学分析中常用的一种图,它能非常直观的显示表达差异的基因或蛋白。在火山图中显示了两个重要的指标(Fold change/p-Value),检验分析出两组样本间显著差异表达的基因后,以log2(fold change)为横坐标,以显著性检验(常用的为T test) P值的负对数-log10(P-value)为纵坐标,利用一定的筛选条件(如大于1.5倍变化且P<0.05),可以筛选出显著差异表达的基因,进行后续研究。

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